DESIGNING SUPERIOR THERAPIES THROUGH AI

EpiVax Therapeutics uses a unique set of  immunoinformatics tools developed over two decades to rapidly design custom therapeutics vaccines for cancer patients.

Image by Markus Spiske
 
Ancer_workflow_08Feb22.png

ANCER

The "Answer" To Cancer

Ancer is an end-to-end, automated neoantigen identification and personalized cancer vaccine design platform [1]. Ancer leverages EpiVax's EpiMatrix and JanusMatrix algorithms, state-of-the-art tools that have been externally validated in several prospective vaccine studies and that are broadly utilized worldwide by pharmaceutical and biotechnology companies [2,3].

 

JANUSMATRIX

In silico removal of inhibitory antigens

The JanusMatrix algorithm, included in the Ancer platform, is a key differentiator of our technology. JanusMatrix, named after Janus — the Roman god of duality, is used to identify putative epitopes which have the potential to cross-react with the human genome [4].

In the case of a vaccines, cross conservation between human epitopes and the antigenic epitopes may indicate that such a candidate utilizes immune camouflage, thereby evading the immune response and making for an ineffective vaccine.

JMX_17Feb22.png